Norfolk Plant Sciences (NPS), a spinout from the John Innes Centre and Sainsbury Laboratory, has received a decision from the USDA Animal and Plant Health Inspection Service (APHIS) determining that its modified tomato is unlikely to pose an increased plant pest risk relative to an appropriate comparator. The decision is expected to enable US home growers to purchase and cultivate the nutritionally enhanced high-anthocyanin purple tomato from 2023. The deregulation means that the purple tomato is not subject to regulations limiting the movement of organisms modified or produced using genetic engineering techniques. The tomato has been modified to produce increased levels of endogenous anthocyanins in fruit with tissue-specific co-expression of the Antirrhinum majus Rosea1 and Delila transcription factors, and to contain a selectable marker that imparts antibiotic (kanamycin and neomycin) resistance using the neomycin phosphotransferase (NPTII) gene.